Understanding Phenylpropanolamine: Potential Side Effects in Dogs

If your pooch is having issues with urinary incontinence or nasal congestion, your vet may prescribe phenylpropanolamine for her. Phenylpropanolamine is the active ingredient in several brand name medications for dogs, including Proin, PPA-RD, Cystolamine and Propalin. While most pups generally tolerate this medication pretty well, it's not without side effects, most of which usually are mild.

Phenylpropanolamine Side Effects for Your Pooch

Phenylpropanolamine is a medication you give your dog orally, either in tablet or liquid form, as directed by your vet. After taking the medicine, your pooch might experience some gastrointestinal upset and loose stools. She could become restless, irritable or possibly aggressive. Her blood pressure or heart rate may increase. She might lose her appetite, experience urine retention or develop tremors when taking the medication. If you notice any of these side effects, discuss them with your vet, who may stop the medication or adjust its dosage, depending on the severity of your pup's symptoms.

Unusual Reactions and Drug Interactions

Some dogs may have an allergic reaction to phenylpropanolamine, exhibiting symptoms such as facial swelling, excessive vomiting, hives and convulsions. Your pooch could even go into a coma. These effects are not normal. If you notice them, you'll need to contact your vet immediately. This medication can interact negatively with other medications including nonsteroidal anti-inflammatory drugs, ephedrine, epinephrine, beta-blockers, monoamine oxidase inhibitors and tricyclic antidepressants. Speak with your vet if your pooch is taking any medications, including vitamins, and if your pup is pregnant or nursing before starting phenylpropanolamine.

Always check with your veterinarian before changing your pet’s diet, medication, or physical activity routines. This information is not a substitute for a vet’s opinion.